A Simple and Efficient Synthesis of Highly Substituted Indeno[1,2-b]pyrrole and Acenaphtho[1,2-b]pyrrole Derivatives by Tandem Three-Component Reactions

作者：Tang, Xiaodong; Zhu, Songlei^*; Ma, Ying; Wen, Ren; Cen, Lanqi; Gong, Panwei; Wang, Jing^*

来源：Molecules, 2018, 23(11): 3031.

DOI：10.3390/molecules23113031

• multi-component reactions
• indeno[1
• 2-b]pyrroles
• acenaphtho[1

A green, convenient and tandem procedure for the efficient synthesis of highly substituted indeno[1,2-b]pyrrole and acenaphtho[1,2-b]pyrrole derivatives by domino three-component reaction of tryptamine/benzylamine, 1,3-dicarbonyl compounds and ninhydrin/ acenaphthenequinone is described. The significant features of this procedure were characterized by mild reaction conditions, high yields, operational simplicity and it being environmentally benign.

• 出版日期2018-11
• 单位徐州医科大学