Advanced age does not affect abdominal wall reconstruction outcomes using acellular dermal matrix: A comparative study using propensity score analysis

作者：Giordano Salvatore; Schaverien Mark; Garvey Patrick B; Baumann Donald P; Liu Jun; Butler Charles E^*

来源：American Journal of Surgery, 2017, 213(6): 1046-1052.

DOI：10.1016/j.amjsurg.2016.10.023

• Hernia
• Abdominal wall
• Elderly
• Advanced age
• Old
• Surgical mesh
• Acellular dermal matrix
• Strattice
• SurgiMend
• Postoperative complications

Background: We hypothesized that elderly patients (>= 65 years) experience worse outcomes following abdominal wall reconstruction (AWR) for hernia or oncologic resection.
Methods: We included all consecutive patients who underwent complex AWR using acellular dermal matrix (ADM) between 2005 and 2015. Propensity score analysis was performed for risk adjustment in multivariable analysis and for one-to-one matching. The primary outcome was hernia recurrence; the secondary outcomes included surgical site occurrence (SSO) and bulging.
Results: Mean follow-up for the 511 patients was 31.4 months; 184 (36%) patients were elderly. The elderly and non-elderly groups had similar rates of hernia recurrence (7.6% vs 10.1%, respectively; p = 0.43) and SSO (24.5% vs 23.5%, respectively; p = 0.82). Bulging occurred significantly more often in elderly patients (6.5% vs 2.8%, respectively; p = 0.04). After adjustment through the propensity score, which included 130 pairs, these results persisted.
Conclusions: Contrary to our hypothesis, elderly patients did not have worse outcomes in AWR with ADM. Surgeons should not deny elderly patients AWR solely because of their age.

• 出版日期2017-6