Admix'em: a flexible framework for forward-time simulations of hybrid populations with selection and mate choice

作者:Cui Rongfeng*; Schumer Molly; Rosenthal Gil G
来源:Bioinformatics, 2016, 32(7): 1103-1105.
DOI:10.1093/bioinformatics/btv700

摘要

We introduce a new forward-time simulator, Admix'em, that allows for rapid and realistic simulations of admixed populations with selection. Complex selection can be achieved through user-defined fitness and mating-preference probability functions. Users can specify realistic genomic landscapes and model neutral SNPs in addition to sites under selection. Admix'em is designed to simulate selection in admixed populations but can also be used as a general population simulator. Usage and examples are in the supplement.

  • 出版日期2016-4-1