Microwave assisted one-pot pseudo four-component synthesis of 2,4,6-trisubstituted pyridines using gamma-MnO2 nanoparticles

Mohammadi Bagher

doi:10.1007/s00706-016-1698-6

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Microwave assisted one-pot pseudo four-component synthesis of 2,4,6-trisubstituted pyridines using gamma-MnO2 nanoparticles

作者：Mohammadi Bagher

来源：Monatshefte fur Chemie, 2016, 147(11): 1939-1943.

DOI：10.1007/s00706-016-1698-6

摘要

This work described an efficient, one-pot pseudo four-component synthesis of 2,4,6-triarylpyridines. This reaction was performed under microwave irradiation and solvent-free conditions in the presence of gamma-MnO2 nanoparticles. Herein 2,4,6-triarylpyridines were synthesized via a simple reaction between benzyl alcohols, acetophenone, and ammonium acetate in the presence of gamma-MnO2 nanoparticles in good to excellent yields. Eco friendly, excellent yields of the product, short reaction times, inexpensive and readily available starting material are the main advantages of this method.