Mitochondrial DNA mutations in Japanese detected by polymerase chain reaction restriction fragment single strand conformation polymorphism analysis

作者：Tawata M^*; Ikegishi Y; Iwase E; Aida K; Onaya T

来源：Genetic Analysis - Biomolecular Engineering, 1997, 14(1): 17-19.

DOI：10.1016/S1050-3862(97)01076-0

• mitochondrial DNA mutations
• PCR-RF-SSCP analysis
• HhaI
• HincII
• Japanese

PCR-restriction fragment-SSCP (PCR-RF-SSCP) analysis of mitochondrial DNA by HhaI/HincII in Japanese revealed 46 polymorphic patterns. The determinations of nucleotide sequence of these 46 patterns revealed 56 mutations compared with the Cambridge Sequence.

• 出版日期1997-3