Blood Pressure during the Immediate Neonatal Transition: Is the Mean Arterial Blood Pressure Relevant for the Cerebral Regional Oxygenation?

作者：Baik Nariae; Urle**erger Berndt; Schwaberger Bernhard; Avian Alexander; Mileder Lukas; Schmoelzer Georg M; Pichler Gerhard

来源：Neonatology, 2017, 112(2): 97-102.

DOI：10.1159/000455965

• Preterm infants
• Term neonates
• Cerebral regional oxygen saturation
• Blood pressure
• Mean arterial blood pressure
• Neonatal transition

Background: Measurement of mean arterial blood pressure (MABP) is feasible during neonatal transition. Objective: The objective of this study was to investigate a potential influence of MABP on the cerebral regional oxygen saturation (crSO(2)) in preterm and term infants during the immediate neonatal transition. Materials and Methods: Preterm and term infants were included in this observational study. The crSO(2) was measured by near-infrared spectroscopy with the INVOS 5100C (Somanetics Corp., Troy, MI, USA) during the immediate neonatal transition (15 min after birth). The near-infrared spectroscopy sensor was applied to the left forehead. Furthermore, a pulse oximeter was applied to monitor arterial oxygen saturation (SpO(2)) and heart rate (HR). Fifteen minutes after birth, blood pressure was measured noninvasively at the left upper arm. Cerebral fraction tissue oxygen extraction (cFTOE) was calculated from SpO(2) and crSO(2). To investigate a potential association between crSO(2) /cFTOE and MABP, we performed a correlation analysis. Results: A total of 462 preterm and term infants (186/292) were included. Mean gestational age was 31.0 +/- 3.5 weeks for preterm infants and 38.9 +/- 0.8 weeks for full term infants. Mean birth weight was 1.591 +/- 630 g in preterm infants and 3.331 +/- 461 g in term infants. There was a significant negative correlation between MABP and cFTOE (rho = -0.19, p = 0.03) in preterm infants but not in term infants (rho = 0.05, p = 0.39). There was no significant correlation between MABP and crSO(2) in either group. Conclusion: MABP has an impact on cerebral oxygenation in preterm infants. Therefore, blood pressure monitoring during the immediate neonatal transition might be relevant for improving cerebral oxygenation especially in preterm infants.

• 出版日期2017
• 单位河北医科大学