A new bergenin derivative from the rhizome of Ardisia gigantifolia

作者：Mu, Li-Hua; Feng, Ju-Qiang; Liu, Ping^*

来源：Natural Product Research, 2013, 27(14): 1242-1245.

DOI：10.1080/14786419.2012.724415

• Ardisia gigantifolia
• bergenin derivatives
• antioxidant activity

One new bergenin derivative, named 11-O-veratroylbergenin (1) along with five known bergenin derivatives, 11-O-(3-O-methylgalloyl) bergenin (2), 11-O-syringylbergenin (3), 11-O-Galloylbergenin (4), 4-O-Galloylbergenin (5) and bergenin (6) were isolated from Ardisia gigantifolia Stapf. Their structures were established on the basis of spectroscopic analysis, especially by means of 1D, 2D-NMR and HR-ESIMS analyses. Compounds 2, 4 and 5 showed significant 2,2-diphenyl-1-picrylhydrazyl (DPPH) free-radical scavenging activity with EC50 9.7, 9.0 and 7.8 mu molL(-1), respectively. They showed more antioxidant activity than the positive control vitamin C (EC50=28.3 mu molL(-1)).

• 出版日期2013-7-1
• 单位中国人民解放军总医院; 天津中医药大学