Aspirin adherence during high-risk pregnancies, a questionnaire study

作者：Abheiden Carolien Nienke Heleen^*; van Reuler Alexandra Vera Ruth; Fuijkschot Wessel Willem; de Vries Johanna Inge Petra; Thijs Abel; de Boer Marjon Alina

来源：Pregnancy Hypertension-An International Journal of Womens Cardiovascular Health, 2016, 6(4): 350-355.

DOI：10.1016/j.preghy.2016.08.232

• Acetylsalicylic-acid
• Adherence
• Aspirin
• Compliance
• High-risk pregnancy
• Hypertensive disorders of pregnancy

Objective: Aspirin reduces the risk of recurrent hypertensive disorders of pregnancy (HD) and fetal growth restriction (FGR). This study examined the non-adherence rates of aspirin in women with high-risk pregnancies.
Study design: All consecutive women between 24 and 36 weeks gestation with an indication for aspirin use during pregnancy were invited for this study. A survey was used which included two validated questionnaires, the simplified medication adherence questionnaire (SMAQ) and the Beliefs and Behaviour Questionnaire (BBQ).
Main outcome measures: To determine the non-adherence rates of aspirin, and to identify the beliefs and behavior concerning aspirin.
Results: Indications for aspirin use during pregnancy were previous HD, FGR, intrauterine fetal death or current maternal disease. Non-adherence rates according to the SMAQ and BBQ were 46.3% and 21.4% respectively. No differences in demographic background or obstetrical characteristics between adherent and non-adherent women could be demonstrated.
Conclusions: Adherence for aspirin in this high-risk population cannot be taken for granted. The nonadherence rates in pregnant women are comparable with the non-adherence rates for aspirin in the non-pregnant population.

• 出版日期2016-10