Determination of Abraham model solute descriptors for isophthalic acid from experimental solubility data in organic solvents at 298 K

作者：Schmidt Amber; Grover Damini; Zettl Heidi; Koshevarova Victoria; Dai Colleen; Zhang Shoshana; Hart Erin; Brumfield Michela; De La Rosa Jennifer; Portillo Valeria; Pugh Ashley; Sanchez Alfredo; Acree William E Jr; Abraham Michael H

来源：Physics and Chemistry of Liquids, 2016, 54(6): 747-757.

DOI：10.1080/00319104.2016.1149178

• Isophthalic acid solubilities
• solubility predictions
• alcohol solvents
• Abraham model
• solute descriptors

Experimental solubilities have been measured for isophthalic acid dissolved in eleven primary alcohol, three secondary alcohol and three alkoxyalcohol solvents at 298K. Results of the experimental measurements, combined with published solubility data for isophthalic acid in ethyl acetate, acetic acid, acetophenone, acetone, cyclohexanone, propyl acetate, N-methyl-2-pyrrolidone and tetrahydrofuran, were used to determine the Abraham model solute descriptors for isophthalic acid. The calculated solute descriptors described the measured solubility data to within an overall average standard deviation of 0.15 log units.

• 出版日期2016-12