A case of colon perforation due to enteropathy-associated T-cell lymphoma

作者：Kim Jun Bong; Kim Seong Hwan^*; Cho Young Kwan; Ahn Sang Bong; Jo Yun Ju; Park Young Sook; Lee Ji Hyun; Kim Dong Hee; Lee Hojung; Jung Yun Young

来源：World Journal of Gastroenterology, 2013, 19(11): 1841-1844.

DOI：10.3748/wjg.v19.i11.1841

• Enteropathy-associated T-cell lymphoma type II
• Intestinal perforation
• Gastrointestinal lymphoma
• Celiac disease

Enteropathy-associated T-cell lymphoma (EATL) is an extremely rare disease, which is often related to gluten-sensitive enteropathy. It is an uncommon intestinal lymphoma with very poor prognosis and high mortality rate. In the absence of specific symptoms or radiological findings, it is difficult to diagnose early. Major complications of EATL have been known as intestinal perforation or obstruction, and only 5 cases of EATL are reported in South Korea. In this study, we report a case of 71-year-old male with symptoms of diarrhea, which later it progressed into cancer perforation of the colon. The initial colonoscopic findings were normal and computed tomography scan demonstrated a segmental wall thickening of the distal ascending colon with nonspecific multiple small lymphnodes, along the ileocolic vessels, but no signs of mass or obstruction. The histologic findings of resected specimen confirmed EATL type II. Patient expired two weeks after the operation. Therefore, we emphasize the need of random biopsy in the presence of normal mucosa appearance on colonoscopy for the early diagnosis of EATL.

• 出版日期2013-3-21