Numerical Comparison between Nonisolated and Isolated Metal-Electrode-Based Dielectrophoresis Cell Separation

作者：Malekshahi Mazdak Rad^*; Ansaroudi Karim; Veladi Hadi; Bahrami Manouchehr

来源：Sensors and Materials, 2013, 25(9): 653-665.

• dielectrophoresis
• cell separation
• interdigitated electrode arrays
• dielectric layer

The effects of electrode isolation on dielectrophoresis (DEP)-based cell separation devices are discussed. In this study, the conventional dielectrophoresis forces using interdigitated electrode arrays are numerically investigated in the presence of a dielectric layer between electrodes and electrolytes and compared with the direct contact model. It is observed that insertion of a dielectric as an isolation layer affects the spectral response of the DEP forces, as a result of the frequency dependence of the fields. The cells under study are live and dead yeast cells and an isolation layer is developed using polydimethylsiloxane (PDMS) elastomer.

• 出版日期2013