ADMETNet: The knowledge base of pharmacokinetics and toxicology network

作者:Xu, Quan; Liu, Ke; Lin, Xingming; Qin, Yangmei; Chen, Linshan; Cheng, Jiao; Zhong, Mindong; He, Qiushun; Li, Yinbo; Wang, Tingwu; Pan, Jianbo; Peng, Menglu; Yao, Lixia; Ji, Zhiliang*
来源:Journal of Genetics and Genomics, 2017, 44(5): 273-276.
DOI:10.1016/j.jgg.2017.04.005

摘要

<正>A good drug or drug candidate should not only interact with its target molecule effectively and specifically,but also be absorbed into the body,distributed to the right location,metabolized into right compounds,and eliminated out of the body in proper manner.The processes of drug getting into and out of the body involve Absorption,Distribution,Metabolism,and Excretion(ADME),which is