Auditory symptom provocation in dental phobia: A near-infrared spectroscopy study

作者：Koechel Angelika; Plichta Michael M; Schaefer Axel; Schoengassner Florian; Fallgatter Andreas J; Schienle Anne^*

来源：Neuroscience Letters, 2011, 503(1): 48-51.

DOI：10.1016/j.neulet.2011.07.058

• Dental phobia
• Auditory stimulation
• NIRS
• SMA
• Parietal cortex

The act of drilling a tooth belongs to the most feared situations of patients suffering from dental phobia. We presented 25 female patients and 24 nonphobic women with the sound of a dental drill, pleasant and neutral sounds. Brain activation was recorded via near infrared spectroscopy in fronto-parietal and premotor areas. The groups differed in supplementary motor area (SMA) recruitment. Relative to controls, the phobics displayed increased oxy hemoglobin while presented with the phobia-relevant sound, but showed comparable activation in the other conditions. As the SMA is engaged in the preparation of motor actions, the increased response in patients might mirror the priming of flight behavior during exposure. We found no indication of an emotional modulation of parietal and dorsomedial prefrontal cortex activation.

• 出版日期2011-9-26
• 单位上海市精神卫生中心