Accelerating preclinical PET-screening: reductive amination with [C-11]methoxybenzaldehydes

作者:Herth Matthias M*; Leth Petersen Sebastian; Lehel Szabolcs; Hansen Martin; Knudsen Gitte M; Gillings Nic; Madsen Jacob; Kristensen Jesper L
来源:RSC Advances, 2014, 4(41): 21347-21350.
DOI:10.1039/c4ra02506g

摘要

We report, herein, a simple and efficient labelling strategy for multiple PET tracer preparation using a common intermediate, which has the potential to accelerate preclinical PET radiotracer screening. This procedure was applied to and compared with a previously published labelling strategy illustrating the advantages of this newly developed combinatorial approach.

  • 出版日期2014