Elucidation of O-phosphoryl and N-phosphoryl amino acids by electrospray ionization tandem mass spectrometry

作者：Zhang JC^*; Cao SX; Xu J; Liao XC; Zhao YF

来源：Chinese Journal of Chemistry, 2004, 22(8): 870-873.

• N-phosphoryl amino acid
• O-phosphoryl amino acid
• electrospray ionization tandem mass spectrometry

Mass spectroscopic characteristics of phosphoryl amino acids were studied in detail by positive and negative electrospray ionization mass spectrometry (ESI-MS) in conjunction with tandem mass spectrometry (MS/MS). Besides N-diisopropyloxyphosphoryl amino acids (N-DIPP-AA), O-phospho- and O-diisopropyloxyphosphoryl amino acids (O-DIPP-AA) were studied and compared to N-DIPP-AA. The fragmentation pathways of [M+H](+), [M+Na](+) and [M-H](-) ions of phosphoryl amino acids were summarized. In addition to several similar patterns, each of them showed its characteristic fragmention.

• 出版日期2004-8
• 单位郑州大学