Misoprostol for induction of labor

作者：Stephenson Megan L^*; Wing Deborah A

来源：Seminars in Perinatology, 2015, 39(6): 459-462.

DOI：10.1053/j.semperi.2015.07.008

• prostaglandin
• cervical ripening
• tachysystole
• cesarean delivery
• vaginal insert

Labor-induction rates have increased considerably in the United States as well as around the world. With up to half of all induced labors requiring cervical ripening, prostaglandins have been utilized to increase induction success and achieve vaginal delivery. Misoprostol, a synthetic prostaglandin El analog has the ability to mimic the changes of spontaneous labor and has been used off label for over 30 years as a labor-induction agent. In the following article, cervical ripening and induction of labor with misoprostol will be discussed. The risks and benefits of misoprostol for ripening and induction and routes of administration will be reviewed, as well as future directions and new developments for its use.

• 出版日期2015-10