Dried blood spots versus sera for detection of rubella virus-specific immunoglobulin M (IgM) and IgG in samples collected during a rubella outbreak in Peru

作者:Helfand Rita F*; Cabezas Cesar; Abernathy Emily; Castillo Solorzano Carlos; Ortiz Ana Cecilia; Sun Hong; Osores Fernando; Oliveira Lucia; Whittembury Alvaro; Charles Myrna; Andrus Jon; Icenogle Joe
来源:Clinical and Vaccine Immunology, 2007, 14(11): 1522-1525.
DOI:10.1128/CVI.00144-07

摘要

Most persons with rubella virus-specific immunoglobulin M (IgM)- or IgG-positive sera tested positive (98% [n = 178] and 99% [n = 221], respectively) using paired filter paper dried blood spot (DBS) samples, provided that DBS indeterminate results were called positive. For persons with IgM- or IgG-negative sera, 97% and 98%, respectively, were negative using DBS.

  • 出版日期2007-11