Mechanisms of nucleic acid translocases: lessons from structural biology and single-molecule biophysics

作者：Hopfner Karl Peter^*; Michaelis Jens

来源：Current Opinion in Structural Biology, 2007, 17(1): 87-95.

DOI：10.1016/j.sbi.2006.11.003

Enzymes that translocate nucleic acids using ATP hydrolysis include DNA and RNA helicases, viral genome packaging motors and chromatin remodeling ATPases. Recent structural analysis, in conjunction with single-molecule studies, has revealed a wealth of new insights into how these enzymes use ATP-driven conformational changes to move on nucleic acids.

• 出版日期2007-2