科研之友
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摘要
Introduction Infections with Angiostrongylus vasorum, originally described as endemic in the southwest of France, is considered an "emerging disease" in Europe and has recently been found in other European countries including Northern Europe. In Austria so far only imported cases have been reported. Although this nematode is usually transmitted from snails to foxes in a silvatic cycle, dogs can ingest the parasite and become infected subclinically or with signs of pulmonary, less frequently systemic, nervous or ocular angiostrogylosis.
Case report The case of a Spaniel dog imported from an endemic region in France which repeatedly returned to his place of origin is presented. During routine examination the dog showed eosinophilia, and faecal examination by the Baer-mann larval migration technique revealed the excretion of A. vasorum. Despite the absence of clinical signs the patient was treated with fenbendazole (50 mg/kg of body mass daily for 6 days) which resulted in the cessation of larval excretion and reduced eosinophilia to a normal level.
Conclusion It is recommended that dogs which have been to endemic areas and dogs which show signs of pulmonary angiostrongylosis (cough, occasionally haemoptysis, dyspnoea, weakness, occasionally signs of cor pulmonale) are examined coproscopically for the excretion of larvae and that positive cases are treated. Besides fenbendazole (daily application for 5-21 days), moxidectin (single application) and milbemycin oxime (weekly application) are effective. Around 3 weeks after treatment the therapeutical effect should be verified by coproscopy.
- 出版日期2010
