A convenient synthesis and spatial structure of 2-aryl-2-oxo-2-phenylbenzo[e]-1,4,2-oxazaphosphinanes

作者：Dimukhametov M N; Mironov V F^*; Mironova E V; Krivolapov D B; Dobrynin A B; Litvinov I A; Musin R Z

来源：Russian Chemical Bulletin, 2013, 62(8): 1882-1891.

DOI：10.1007/s11172-013-0271-2

• alpha-aminophosphinic acid
• 1,4,2-oxazaphosphinane
• intramolecular Pudovik reaction
• diastereomers
• spatial structure
• conformation

Phosphorylation of 2-arylideneaminophenol with dichlorophenylphosphine in the presence of triethylamine and subsequent treatment with water led to stereoisomeric derivatives of 3-aryl-2-oxo-2-phenylbenzo[e]-1,4,2-oxazaphosphinanes, which were separated by column chromatography to the individual diastereomers. The structure of stereoisomers was established by NMR spectroscopy and X-ray crystallography.

• 出版日期2013-8