摘要

Dynamic bone scanning with Tc-99m-labeled diphosphonates and F-18-labeled sodium fluoride provides functional information sensitive for subtle changes in bone turnover and perfusion, which assists the clinical management of numerous osseous pathologies. This article reviews the mechanisms of uptake of Tc-99m-labeled diphosphonates and F-18-sodium fluoride and discusses and compares the performance of these bone-seeking radiotracers for clinical and research applications, using dynamic and multiple-time-point imaging protocols and quantitative techniques.

  • 出版日期2013-4-1

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