An efficient synthesis of enol phosphates via organic base-promoted addition of phosphites to 4-oxo-enoates

作者：Zhu, Xiao-Yu; Chen, Jia-Rong; Lu, Liang-Qiu^*; Xiao, Wen-Jing

来源：Tetrahedron, 2012, 68(30): 6032-6037.

DOI：10.1016/j.tet.2012.05.021

• Hydrophosphorylation
• 4-Oxo-enonate
• Enol phosphate
• High stereoselectivity

A TMG catalyzed, practical and efficient hydrophosphorylation of 4-oxo-enoates by diethyl or diphenyl phosphite has been described. This protocol allows a convenient access to a variety of enol phosphates under mild conditions in good yield with excellent stereoselectivity.

• 出版日期2012-7-29
• 单位华中师范大学