The sensitivity of direct identification from positive BacT/ALERT (TM) (bioMerieux) blood culture bottles by matrix-assisted laser desorption ionization time-of-flight mass spectrometry is low

作者：Szabados F^*; Michels M; Kaase M; Gatermann S

来源：Clinical Microbiology and Infection, 2011, 17(2): 192-195.

DOI：10.1111/j.1469-0691.2010.03229.x

• BACTEC
• BacTALERT
• blood culture
• direct diagnostic
• MALDI-TOF MS

P>Recently, matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been presented as a novel method for the direct identification of bacteria from positive blood culture bottles. The rate of the MALDI TOF MS-based identification in the present study from positive BacT/ALERT (bioMerieux, Marcy l'Etoile, France) blood culture bottles was 30%, which is far below the previously reported sensitivities using the BACTEC (Becton Dickinson, Franklin Lakes, NJ, USA) system. We also found evidence that the Biotyper algorithm did not identify a second pathogen in cases of positive BacT/ALERT blood culture bottles containing two different species.

• 出版日期2011-2