Anthracene excimer-based "turn on" fluorescent sensor for Cr3+ and Fe3+ ions: Its application to living cells

作者：Erdemir Serkan^*; Kocyigit Ozcan

来源：Talanta, 2016, 158: 63-69.

DOI：10.1016/j.talanta.2016.05.017

• Anthracene
• Benzothiazole
• Fluorescent
• Trivalent
• Sensor

A novel anthracene based fluorescent probe containing benzothiazole group (BFA) was designed and synthesized. The cation binding properties of BFA were studied in the presence of various cations. Both UV-vis and fluorescence spectroscopic studies indicated that BFA was highly sensitive and selective toward trivalent cations (Cr3+ and Fe3+), while there was no response to monovalent, divalent cations and also Al3+ ion. The interaction of BFA with Cr3+ and Fe3+ caused a significant enhancement in emission intensity due to the combination of a unique anthracenyl static excimer formation, the restricted C=N isomerization and the suppression of highly efficient photoinduced electron transfer (PET) process. The detection limits of BFA for Cr3+ and Fe3+ were 0.46 and 0.45 mu M, which presented a pronounced sensitivity toward Cr3+ and Fe3+, respectively. Also, possible utilization of BFA as bioimaging fluorescent probe to detect Cr3+ and Fe3+ in human prostate cancer cell lines was observed by confocal fluorescence microscopy.

• 出版日期2016-9-1