Studies toward the Biomimetic Total Synthesis of (-)-PF-1018

作者：Webster Robert; Gaspar Boris; Mayer Peter; Trauner Dirk^*

来源：Organic Letters, 2013, 15(8): 1866-1869.

DOI：10.1021/ol400508s

Pericyclic reaction cascades are unparalleled in their ability to quickly generate complex structures with excellent stereocontrol. Herein, the use of a biomimetic Stifle/8 pi electrocyclization/Diels-Alder cascade to successfully assemble the core structure of (-)-PF-1018 is reported.

• 出版日期2013-4-19