科研之友
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摘要
The potassium tert-butoxide. mediated deprotonation of two difluoromethyl aryl ketones in the presence of aryl aldehydes in anhydrous dimethylformamide (DMF), provides an efficient and stereoselective synthesis of anti-2,2-difluoropropane-1,3-diols. Both symmetrical and unsymmetrical diols could be prepared in moderate to good yields from readily available starting materials.
- 出版日期2010-11-2
