Age and gender, two key factors in the associations between physical activity and strength during the ageing process

作者：Gomez Cabello Alba^*; Carnicero Jose A; Alonso Bouzon Cristina; Angel Tresguerres Jesus; Alfaro Acha Ana; Ara Ignacio; Rodriguez Manas Leocadio; Garcia Garcia Francisco Jose

来源：Maturitas, 2014, 78(2): 106-112.

DOI：10.1016/j.maturitas.2014.03.007

• Ageing
• Skeletal muscle
• Exercise
• Hormones

Objectives: The aims of this study were to identify if the associations of physical activity (PA) and muscle strength may vary throughout the ageing process; to study the differences among genders in the relationships between PA and strength in elderly people and to test whether these differences are explained by the hormonal, nutritional and inflammatory status. %26lt;br%26gt;Study design: A total of 1741 people %26gt;= 65 years of age participated in this cross-sectional study. %26lt;br%26gt;Main outcome measures: Upper- and lower-limbs maximal voluntary isometric strength was obtained using standardized techniques and equipment. PA was recorded by a validated questionnaire. The associations of PA with strength were assessed using generalized linear regression models with a Gammadistributed dependent variable. %26lt;br%26gt;Results: A significant gender by PA interaction was found for all strength-related variables (all P%26lt;0.01). Moreover, when sexual hormones, albumin or C-Reactive protein were taken into account in the model, the resulis did not significantly change. In women, PA was positively associated with upper and lowerbody strength; however in men, PA was only associated with grip and knee strength (both P%26lt; 0.01). Higher strength values were associated with higher levels of PA, especially in women. However, this tendency had a different pattern across the age range, showing a stronger association in the %26apos;young%26apos; elderly compared with the %26apos;old%26apos; elderly. %26lt;br%26gt;Conclusion: Higher levels of PA are related to greater muscle strength, especially in women and those who were younger.

• 出版日期2014-6