A Novel Twist in Membrane dePHormation

作者:Krauss Michael*; Haucke Volker
来源:Developmental Cell, 2014, 31(1): 3-4.
DOI:10.1016/j.devcel.2014.09.016

摘要

Bin-Amphiphysin-Rvs (BAR) domain-containing proteins form oligomeric assemblies that aid membrane remodeling. In this issue of Developmental Cell, Pang et al. (2014) show that the BAR domain of ACAP1, although architecturally similar to other BAR domains, cooperates with its neighboring pleckstrin homology domain to deform membranes and facilitate endosomal recycling.

  • 出版日期2014-10-13