A dual-response naphthofluorescein-based fluorescent probe for multiple-channel imaging of cysteine/homocysteine in living cells

作者：Yue, Xiuxiu; Li, Wenxiu; Chen, Wenqiang^*; Zhang, Liangliang^*; Li, Guofang; Sheng, Jiarong^*

来源：Tetrahedron Letters, 2018, 59(23): 2232-2237.

DOI：10.1016/j.tetlet.2018.04.017

• Fluorescent probe
• Naphthofluorescein-based
• Cysteine (Cys)
• Homocysteine (Hcy)

A naphthofluorescein-based fluorescent probe with two independent reaction sites (nitro-2,1,3-benzoxa-diazole and acrylate moiety) was developed. Integrating these two reaction sites into a single molecule not only can guarantee the selective detection of Cys/Hcy in an elegant fashion, but also can enable Cys/Hcy detection in a multiple-channel responsive manner.

• 出版日期2018-6-6
• 单位南宁师范大学; 广西师范大学