High-Density Lipoprotein Cholesterol Levels in Middle-School Children: Association with Cardiovascular Risk Factors and Lifestyle Behaviors

作者：Flynn Shannon E; Gurm Roopa; DuRussel Weston Jean; Aaronson Susan; Gakenheimer Lindsey; Smolarski Joseph; Simhaee Daniel; Corriveau Nicole; Goldberg Caren; Eagle Taylor; Rao Ravi M; Eagle Kim A; Jackson Elizabeth A^*

来源：Pediatric Cardiology, 2014, 35(3): 507-513.

DOI：10.1007/s00246-013-0814-1

• Childhood obesity
• Diet
• Physical activity
• Cardiovascular risk factors
• Community health

To examine factors associated with low high-density lipoprotein cholesterol (HDL-C) levels among middle school children. HDL-C levels were the primary outcome of interest. A total of 1,104 middle-school children (mean age 11.6 years, 51.2 % female) were included in this analysis, of whom 177 (16 %) had an HDL-C level a parts per thousand currency sign40 mg/dL. More than half of those with low HDL-C were overweight or obese (62.2 %) and had greater systolic and diastolic blood pressure, triglyceride (TRG) levels, and low-density lipoprotein cholesterol levels compared with children with an HDL-C level > 40 mg/dL. Among those with an HDL-C a parts per thousand currency sign 40 mg/dL, 35 % also had body mass index a parts per thousand yen85 % and TRG levels a parts per thousand yen150 mg/dL. Exercise habits were significantly associated with HDL-C level, whereas sedentary behaviors, such as screen time, were not significantly associated with HDL-C level. Fruit and vegetable intake was also not significantly associated with HDL-C level. Children with low HDL-C levels are more likely to be overweight and to have other physiological indicators of increased cardiovascular risk. Further research is needed to determine if school-based interventions can result in long-term improvements in HDL-C.

• 出版日期2014-3