Secondary prevention for improvements in limb hemiplegia after stroke

作者:Wang, Minjuan*; Li, Yajun*; Li, Lei; Huang, Huiyun; Huang, Lingjuan; Ni, Yaping; Shi, Yingpeng; Wang, Xia
来源:International Journal of Clinical and Experimental Medicine, 2017, 10(6): 9370-9375.

摘要

Objective: To explore the efficacy of secondary prevention on improvements in limb hemiplegia in stroke patients, and to lay a scientific foundation for clinical diagnosis and management. Methods: A total of 96 patients initially-diagnosed as having upper-limb hemiparesis after stroke, who were admitted to our hospital from October 2012 to July 2015, were randomly divided into the treated group (n=48) and the control group (n=48). The treated group received early medical treatment as secondary prevention, with adjunctive rehabilitation therapy, to control blood pressure, glucose and lipids, and anti-platelet aggregation whereas the control group received physical rehabilitation training alone. The motility of the wrist joints and the hand on the hemiplegic side, and the activities of daily living (ADL) of the patients were assessed using the Barthel Index (BI), functional comprehensive assessment (FCA), and simplified fugl-Meyer assessment scale (U-FMA) within 24 hours before treatment and 3 months after treatment, respectively. After the first three months of treatment was completed, the patients in the control group began to receive secondary prevention for the following three months, followed by assessments on the motility of their limbs on the hemiplegic side. Finally, the efficacy of the intervention therapies was compared between the groups. Results: Compared with those in the control group, the motility of the wrist joints and hands, and activities of daily living (ADL) were improved significantly in the patients in the treated group (n=48) (P<0.05). Significant improvements were also observed in the patients in the control group after they received the additional secondary prevention in the latter three months (P<0.05). Conclusion: The medical treatment as early secondary prevention can significantly improve the recovery of the motility in the affected limbs of the patients with stroke.