Utility of a Commercial PCR Assay and a Clinical Prediction Rule for Detection of Toxigenic Clostridium difficile in Asymptomatic Carriers

作者：Donskey Curtis J^*; Sunkesula Venkata C K; Jencson Annette L; Stone Nimalie D; Gould Carolyn V; McDonald L Clifford; Samore Matthew; Mayer Jeanmarie; Pacheco Susan; Sambol Susan; Petrella Laurica; Terry Deborah; Gerding Dale N

来源：Journal of Clinical Microbiology, 2014, 52(1): 315-318.

DOI：10.1128/JCM.01852-13

A commercial PCR assay of perirectal swab specimens detected 17 (68%) of 25 asymptomatic carriers of toxigenic Clostridium difficile, including 93% with skin and/or environmental contamination. A clinical prediction rule, followed by PCR screening, could be used to identify carriers at high risk of C. difficile shedding.

• 出版日期2014-1