A Wacky Bridge to mTORC1 Dimerization

作者：Montagne Jacques^*

来源：Developmental Cell, 2016, 36(2): 129-130.

DOI：10.1016/j.devcel.2016.01.006

The activity of the mTORC1 protein complex depends on multiple metabolic inputs that regulate dimerization, recruitment to the lysosome, and activation. In this issue of Developmental Cell, David-Morrison et al. (2016) show that the Drosophila protein Wacky and its mammalian counterpart WAC act as adaptors in the process of mTORC1 dimerization.

• 出版日期2016-1-25
• 单位中国地震局