科研之友
微信
新浪微博
Facebook
分享链接
摘要
Adiponectin is an adipokine hormone that influences several metabolic functions including glucose utilization, lipogenesis, energy homeostasis and immunity by signaling through two distinct receptors, AdipoR1 and AdipoR2. AdipoR1 is abundantly expressed in skeletal muscle, whereas AdipoR2 is predominantly expressed in the liver. AdipoR1 and AdipoR2 genes are ubiquitously expressed in chicken tissues and that their expression is altered by feed deprivation in the anterior pituitary gland and adipose tissue. Adiponectin and its receptors expressed in chicken testis. Suggesting that adiponectin either produced locally or from other sources can influence testicular function. These findings indicate that sexual maturation is associated with the up-regulation of adiponectin receptor gene expression in the chicken testis. Also, adiponectin, AdipoR1 and AdipoR2 mRNAs are expressed in chicken theca and granulose cells from preovulatory follicles. Adiponectin is highly expressed in theca cells as compared to granulose cells and could be involved in the development of chicken preovulatory follicle. Differences in the adiponectin expression level observed in different tissues suggest that the adiponectin gene has broad functions in the metabolism process. In order to reveal the function and mechanism of action of adiponectin in life, more considerable and penetrating work should be pursued.
- 出版日期2011-5
