Microwave-assisted synthesis of 1,3-benzodioxole derivatives from catechol and ketones or aldehydes

作者：Pingali Subramanya R K; Jursic Branko S^*

来源：Tetrahedron Letters, 2011, 52(34): 4371-4374.

DOI：10.1016/j.tetlet.2011.03.063

• Benzodioxoles
• Microwave-assisted reactions
• Catechol protection
• Carbonyl protection

An efficient synthetic procedure for the preparation of a diverse library of 1,3-benzodioxoles was developed by applying controlled microwave heating in comparison with currently available conventional heating. Reactions were completed in less than 3 h. The isolation of product is simple, the isolated yields are good to excellent, and this method is applicable to large scale production.

• 出版日期2011-8-24