MR Enterography in Crohn's disease complicated with enteroenteric fistula

作者：Erden Ayse^*; Unal Sena; Akkaya Habip Eser; Onay Mehmet; Toruner Murat; Gencturk Zeynep Biyikli; Kartal Aysun Caliskan

来源：European Journal of Radiology, 2017, 94: 101-106.

DOI：10.1016/j.ejrad.2017.06.012

• Crohn's disease
• Fistula
• Magnetic resonance imaging
• Disease activity
• Disease complications

Objective: In this retrospective study, we aimed to evaluate MR enterography (MRE) findings, MR index of activity (MaRIA) and laboratory markers in Crohn patients with enteroenteric fistula.
Methods: Institution's electronic medical records (laboratory, pathology, ileocolonoscopy results and discharge summary) were reviewed and MR images retrieved from the PACS were reanalyzed in Crohn patients assessed at Gastroenterology Clinic of our university between July 2011 and July 2016. MR enterography and clinic parameters of 38 Crohn patients with enteroenteric fistula and 48 Crohn patients without enteroenteric fistula were compared.
Results: Of the findings, perienteric inflammation was seen only in fistula group. The mean wall thickness was significantly greater; perienteric fluid, mural hyperenhancement, cecal contraction, thickening of ileocecal valve, and colonic involvement were significantly more common in fistula patients. There was no significant difference between groups with regards to MaRIA index and perianal disease. In patients with enteroenteric fistula, there was significant association between the presence of hypoalbuminemia and presence of ileitis at ileocolonoscopy. In the overall study population, there was a positive correlation between the MaRIA and CRP values at the time of the MRE.
Conclusions: Perienteric mesenteric inflammation and fluid collection are common in enteroenteric fistulization. MaRIA indices and laboratory findings of patients with enteroenteric fistula are not significantly different from those without fistulas.

• 出版日期2017-9