Does a screening questionnaire for familial and hereditary colorectal cancer risk work in a health insurance population?

作者：Pieper C^*; Kolankowska I; Joeckel K H

来源：European Journal of Cancer Care, 2012, 21(6): 758-765.

DOI：10.1111/j.1365-2354.2012.01358.x

• colorectal cancers
• familial risk
• hereditary risk
• risk assessment
• questionnaire
• prevention

PIEPER C., KOLANKOWSKA I. & JOCKEL K.-H. (2012) European Journal of Cancer Care 21, 758-765 Does a screening questionnaire for familial and hereditary colorectal cancer risk work in a health insurance population? The aim of our study was to evaluate actual prevalence, uptake and first experiences with a questionnaire developed for early detection of colorectal cancer (CRC) in persons with familial/hereditary risk. A cross sectional study in an insurance population aged 30-54 years was conducted. Subjects with ICD-10 codes C00 to C97 and D37 to D48 were excluded. A standardised questionnaire was sent to 12 139 subjects. Three months later, subjects with a reported family history were followed by a second questionnaire. An additional telephone survey was performed to validate responses. Nineteen per cent met the inclusion criteria (mean age 45 +/- 7 years, 38% men). Three hundred and seventy-three subjects (16%) were followed by a second questionnaire. Of these, 248 (66%) returned. Forty-four per cent were already aware of their increased risk of developing CRC. Awareness was associated with knowledge of CRC. One hundred subjects (41%) reported that they had informed their general practitioner (GP) or gastroenterologist. A colonoscopy or stool test was recommended to 92. Subjects who found out about their increased risk for the first time, reported significantly less frequent physician contact (GP: 20% vs. 34%, gastroenterologist: 8% vs. 21%). Results indicate that there is a need for a structured, person at risk-adapted, statutory early detection program.

• 出版日期2012-11
• 单位河北医科大学