Mutations altering the specificity of the sensor RNA encoded by the Bacillus subtilis pbuE gene

作者:Lobanov K V*; Korol'kova N V; Eremina S Yu; Lopes L Errais; Proshkin S A; Mironov A S
来源:Russian Journal of Genetics, 2007, 43(6): 712-176.
DOI:10.1134/S1022795407060178

摘要

Site-directed mutagenesis was used to study the leader region of the Bacillus subtilis pbuE gene, which codes for adenine-specific sensor RNA. Two nucleotide substitutions, 70U -> C and A 100 -> G, in the conserved region (A box) of the leader changed the specificity of the sensor RNA in vivo: guanine acted as a positive transcription effector in place of adenine.

  • 出版日期2007-6

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