Development of exclusively cutaneous sarcoidosis in patient with rheumatoid arthritis during treatment with etanercept

作者：Horta Barbosa Vieira Marcella Amaral; Ramos Saraiva Maria Isabel; Leite da Silva Larissa Karine; Fraga Rafael Cavanellas; Kakizaki Priscila; Sakai Valente Neusa Yuriko

来源：Revista da Associacao Medica Brasileira, 2016, 62(8): 718-720.

DOI：10.1590/1806-9282.62.08.718

• sarcoidosis
• tumor necrosis factor-alpha
• chronic granulomatous disease
• rheumatoid arthritis

We report the case of a patient with rheumatoid arthritis who, after 2 months of treatment with etanercept, showed disseminated asymptomatic violaceous papules. Biopsy of the skin lesion showed chronic granulomatous dermatitis with negative staining for fungi and acid-fast bacilli (AFB). After discontinuation of etanercept, the patient's condition improved. Although apparently paradoxical, cases of cutaneous and systemic sarcoidosis after anti-TNF medications have been reported in the literature, with very few cases presenting exclusive cutaneous involvement.

• 出版日期2016-11