Detecting Ni(II) in aqueous solution by 3-(2-pyridyl)-[1,2,3]triazolo[1,5-a]pyridine and dimethyl-beta-cyclodextrin

作者：Jullian Carolina^*; Fernandez Sandoval Samuel; Rojas Aranguiz Max; Gomez Machuca Horacio; Salgado Figueroa Paola; Celis Barros Cristian; Zapata Torres Gerald; Adam Rosa; Abarca Beier

来源：Carbohydrate Polymers, 2014, 107: 124-131.

DOI：10.1016/j.carbpol.2014.02.043

• Cyclodextrin
• Pyridyltriazolopyridine
• Fluorescence
• Ni(II)
• Sensor

A new supramolecular sensitizer for nickel(II) ion in aqueous solution based on a pyridyltriazolopyridine-cyclodextrin inclusion complex is proposed. The inclusion complexation behavior, characterization and binding ability of pyridyltriazolopyridine (PTP) with dimethyl-beta-cyclodextrin (DM beta CD) has been investigated both in solution and solid state by means of absorption, fluorescence, H-1 NMR, DSC, and molecular modeling methods. The stoichiometry of the inclusion complex is 1:1, and the thermodynamic studies indicate that the inclusion of PTP is mainly an entropic driven process. The 2D NMR studies revealed that the pyridyl-triazolopyridine is included by both sides of cyclodextrin which are in good agreement with the docking results. The fluorescence changes upon addition of divalent cations to the inclusion complex indicate a high selectivity and sensitivity for Ni2+ by fluorescence quenching in neutral aqueous solution.

• 出版日期2014-7-17