The Relation between the Duty Cycle and Anesthetic Effect in Lidocaine Iontophoresis Using Alternating Current

作者：Wakita Ryo^*; Nakajima Atsushi; Haida Yu; Umino Masahiro; Fukayama Haruhisa

来源：Pain Practice, 2011, 11(3): 261-266.

DOI：10.1111/j.1533-2500.2010.00418.x

• anesthesia
• local
• iontophoresis
• alternating current (AC)
• pain threshold
• pain assessment

We assessed the effect of the duty cycle on the anesthetic effect during lidocaine alternating current (AC) iontophoresis. A solution of 2% lidocaine was delivered to the medial antecubital skin for 20 minutes using AC iontophoresis with a duty cycle of 60%, 70%, or 80%. The von Frey test was then performed to evaluate the anesthetic effect. In the groups treated with a duty cycle of 80% or 70% the touch thresholds (TT) were significantly elevated from 0 minutes to 30 minutes and from 0 minutes to 20 minutes. TT were significantly elevated at 0 minutes in the group treated with a 60% duty cycle. The anesthetic effect was significantly enhanced in a duty cycle-dependent manner.

• 出版日期2011-6