Asymmetric Synthesis of Planar Chiral Ferrocenes by Enantioselective Intramolecular C-H Arylation of N-(2-Haloaryl)ferrocenecarboxamides

作者：Liu Lantao^*; Zhang An An; Zhao Rui Juan; Li Feng; Meng Tuan Jie; Ishida Naoki; Murakami Masahiro; Zhao Wen Xian

来源：Organic Letters, 2014, 16(20): 5336-5338.

DOI：10.1021/ol502520b

The palladium-catalyzed intramolecular C-H arylation reaction of N-(2-bromoaryl)ferrocenecarboxamides furnishes planar chiral ferrocene derivatives. TADDOL-derived phosphoramide ligands induce enantioselectivities ranging from 91:9 to 98:2 er.

• 出版日期2014-10-17
• 单位商丘师范学院