Binding properties of mono- and dimeric pyridine dicarboxamide ligands to human telomeric higher-order G-quadruplex structures

作者:Saintome C; Alberti P; Guinot N; Lejault P; Chatain J; Mailliet P; Riou J F; Bugaut A
来源:Chemical communications, 2018, 54(15): 1897-1900.
DOI:10.1039/c7cc07048a

摘要

A new dimeric ligand binds telomeric contiguous G4s, displacing the single-stranded DNA binding RPA more efficiently than its monomeric counterpart.

  • 出版日期2018-2-21