作者：Turlington Mark; DeBerardinis Albert M; Pu Lin*
来源：Organic Letters, 2009, 11(11): 2441-2444.
DOI：10.1021/ol900667g
摘要
A novel H(8)BINOL-based chiral ligand (S)-3 is found to catalyze the alkyl propiolate addition to aliphatic aldehydes in the presence of ZnEt(2) and Ti(O(i)Pr)(4) at room temperature with excellent enantioselectivity (89-97% ee).
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