Development of a voltammetric procedure for assay of thebaine at a multi-walled carbon nanotubes electrode: quantification and electrochemical studies

作者：Rezaei Behzad^*; Damiri S

来源：Journal of Solid State Electrochemistry, 2010, 14(6): 1079-1088.

DOI：10.1007/s10008-009-0921-3

• Multi-walled carbon nanotube
• Thebaine
• Adsorptive stripping voltammetry
• Electrochemical impedance spectroscopy

The study of electrochemical behavior and determination of thebaine (THEB), an opiate alkaloid, is described on a multi-walled carbon nanotube (MWCNT) modified glassy carbon electrode by adsorptive stripping voltammetry and electrochemical impedance spectroscopy. The results indicated that MWCNT electrodes remarkably enhance electrocatalytic activity toward the oxidation of THEB in a wide pH range of 2.0-10.0, and it shows two irreversible and diffusion-controlled anodic peaks. Then, a sensitive, simple, and time-saving cyclic voltammetric procedure was developed for the analysis of THEB in human urine samples. Under optimized conditions, the oxidation peak has two linear dynamic ranges of 1.0-80.0 and 100.0-600.0 mu M, with detection limit of 0.23 mu M and a precision of < 4% (relative standard deviation for eight analysis).

• 出版日期2010-6