Aggressive sinonasal natural killer/T-cell lymphoma with hemophagocytic lymphohistiocytosis

作者：Turner Justin H^*; Loyo Myriam; Lin Sandra Y

来源：American Journal of Otolaryngology, 2012, 33(1): 188-191.

DOI：10.1016/j.amjoto.2011.05.003

Extranodal natural killer/T-cell lymphoma of the nasal cavity is a rare malignancy with poor overall prognosis. We report the case of a rapidly fatal natural killer/T-cell lymphoma of the nasal cavity complicated by the concominant development of hemophagocytic lymphohistiocytosis. This disorder is marked by clinical findings such as fever and splenomegaly, a multitude of abnormal laboratory findings, and a profound proliferation of circulating macrophages. Left untreated, multi-organ failure and death are common. Prompt diagnosis is essential to the successful management of this disorder and for subsequent recovery.

• 出版日期2012-2