Active surveillance for low-risk prostate cancer: knowledge, acceptance and practice among urologists

作者：Gorin M A; Eldefrawy A; Ekwenna O; Soloway M S^*

来源：Prostate Cancer and Prostatic Diseases, 2012, 15(2): 177-181.

DOI：10.1038/pcan.2011.57

• active surveillance
• survey
• watchful waiting

BACKGROUND: This study aimed to survey urologists regarding their knowledge, acceptance and practice of active surveillance (AS) for low-risk prostate cancer. %26lt;br%26gt;METHODS: An email-based survey was distributed to 4987 urologists. Respondents were surveyed regarding their knowledge and acceptance of AS. Those who felt AS was a reasonable strategy were asked their opinions on the criteria for AS enrollment and the details of their practice of AS. Respondents who felt AS was not a reasonable alternative were queried as to the reasons why. %26lt;br%26gt;RESULTS: A total of 425 (9%) urologists successfully completed the survey and 387 (91%) were both familiar with AS and aware that AS differed from watchful waiting. Of this latter group, 370 (96%) respondents felt AS was a reasonable management strategy, 95% of whom manage patients with this approach. A minority of respondents (6%) felt that patients with a PSA%26gt;10 ng ml(-1) were eligible for AS. Further, most participants (74%) felt that patients required a Gleason score %26lt;= 6. There was little agreement on the timing of follow-up biopsies. Respondents who objected to AS were most commonly concerned with missing an opportunity for curative treatment (76%) and the risk of tumor undergrading (65%). %26lt;br%26gt;CONCLUSIONS: The majority of participants were knowledgeable and accepting of AS. Respondents were in relative agreement regarding the PSA and Gleason score criteria for AS enrollment. In contrast, there was a lack of agreement on the timing of follow-up biopsies. In the future, comparative studies are required to determine the optimal enrollment criteria and follow-up protocol for patients managed with AS.

• 出版日期2012-6