Mitomycin extravasation after postoperative instillation

作者：Panach Navarrete Jorge^*; Ferrondis Cortes Cristina; Angeles Sales Maicas Maria; Maria Martinez Jabaloyas Jose

来源：Archivos Espanoles de Urologia, 2015, 68(7): 633-636.

• Bladder perforation
• Cystectomy Eosinophilic cystitis
• Mitomycin
• Transurethral resection

OBJECTIVE: To present the therapeutic management of severe complications related to postoperative mitomycin extravasation.
METHODS: Description of clinical cases, medical and surgical management and pathologic results of surgical specimens.
RESULTS: We report two cases of patients with extra vesical mitomycin leakage after postoperative instillation. No bladder perforation was evident during tumor surgery. In both cases radical cystectomy was required.
CONCLUSIONS: Postoperative mitomycin instillation may have undesirable consequences. The possible problems derived from its administration must be known, and each case must be individualized before administering this chemotherapy.

• 出版日期2015-9