One-pot cascade approach to 1,3 '-bipyrrole derivatives from trisubstituted olefins with tosylmethyl-isocyanide (TosMIC)

作者：Qiu, Fangli; Wu, Jianwei; Zhang, Yaohong; Hu, Miao; Yu, Yongping^*

来源：Tetrahedron Letters, 2012, 53(4): 446-448.

DOI：10.1016/j.tetlet.2011.11.076

• 1.3'-Bipyrrole
• Toluenesulfonyl-methyl isocyanide
• (TosMIC)
• Trisubstituted olefins

A novel and effective route for the synthesis of 1,3'-bipyrrole derivatives by multisubstituted olefins with TosMIC was developed. Moreover, the synthetic protocol was simple and the reaction conditions were mild. A possible mechanism was proposed.

• 出版日期2012-1-25
• 单位浙江大学; 台州学院