NanoEHS - defining fundamental science needs: no easy feat when the simple itself is complex

作者：Grassian Vicki H; Haes Amanda J; Mudunkotuwa Imali A; Demokritou Philip; Kane Agnes B; Murphy Catherine J; Hutchison James E; Isaacs Jacqueline A; Jun Young Shin; Karn Barbara; Khondaker Saiful I; Larsen Sarah C; Lau Boris L T; Pettibone John M; Sadik Omowunmi A; Salehm Navid B; Teaguen Clayton

来源：Environmental Science: Nano , 2016, 3(1): 15-27.

DOI：10.1039/c5en00112a

Nanotechnology is no longer in its infancy and has made significant advances since the implementation of the National Nanotechnology Initiative (NNI) in 2000. Incorporation of nanotechnology in many fields including information technology, medicine, materials, energy, catalysis and cosmetics has led to an increase in engineered nanomaterial (ENM) production, and consequently, increased nanomaterial use. In comparison, the generation of concrete and consistent evidence related to the environmental health and safety of nanomaterials (NanoEHS) is lacking. The main factors contributing to the slower progress in NanoEHS versus conventional EHS are related to the complexity, property transformations, life cycles and behavior of nanomaterials even in carefully controlled environments. Therefore, new systematic, integrated research approaches in NanoEHS are needed for overcoming this complexity and bridging current knowledge gaps. A workshop on "NanoEHS: Fundamental Science Needs" brought together scientists and engineers to identify current fundamental science challenges and opportunities within NanoEHS. Detailed discussions were conducted on identifying the fundamental properties that are critical in NanoEHS, differentiating between conventional and NanoEHS studies as well as understanding, the effect of dynamic transformations on nanometrology, role of dosimetry and mechanistic data gaps in nanotoxicology. An important realization that even simple nanoscale materials can be complex when considering NanoEHS implications was noted several times during the workshop. Despite this fact, a number of fundamental research areas to further the scientific foundation to address NanoEHS needs are suggested.

• 出版日期2016
• 单位东北大学